Preheat oven to 400 degrees.

In a 9 x 11 glass pyrex dish, spray with non-stick spray.

In a large pan over medium heat, add ground beef, garlic powder, onion powder, sea salt, and pepper. Drain excess grease.

Spread the ground beef evenly in the glass dish, and then cover with shredded cheese.

In a medium sized bowl, add in Bisquick, eggs, and a little bit of milk. Start stirring mixture with whisk, and then slowly add in the rest of the milk. This will help release any type of small lumps that might occur. **NOTE: The batter is very loose, so don't be alarmed!**

Pour mixture on top of cheese layer.

Place in the oven for approximately 25 - 30 minutes, or until the cheese layer is nice and bubbly brown.

Allow to cool before service.